Further pharmacological activity of Oleuropein includes diverse healing properties due to its vasodilatory [1], anti-platelet aggregation [2], hypotensive [3, 4], anti-rheumatic [1], diuretic [3] and antipyretic [5] effects. Prevention of free radical formation by Oleuropein occurs through its ability to chelate metal ions, such as Cu and Fe, which catalyze free radical generation reactions [6], and through its inhibitory effect on several inflammatory enzymes like lipoxygenases [2]. Previously, Oleuropein was reported to have an anti-hyperglycemic effect in diabetic rats [7]. Oleuropein inhibits hyperglycemia and oxidative stress induced by diabetes, which suggests that administration of Oleuropein is helpful in the prevention of diabetic complications associated with oxidative stress [8].

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  Low-density lipoprotein oxidation is inhibited in vitro by olive oil constituents.
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