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Ancora et al. [1] have shown that the phenol components of olive oil have a direct antioxidant action on skin, especially Oleuropein, which acts as a free radical scavenger at the skin level. Recently, Kimura and Sumiyoshi [2] suggested that the preventative effects of olive leaf extracts and Oleuropein on chronic UVB-induced skin damage and carcinogenesis and tumor growth may be due to inhibition of the expression of VEGF, MMP-2, MMP-9, and MMP-13 through a reduction in COX-2 levels.